Bicyclic Hexahydroaporphine and 1-Benzyloctahydroisoquinoline Therapeutic Compositions and Processes for Utilizing Said Compositions

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Authors
Roche, Victoria F.
Ohia, Sunny E.
Roche, Edward B.
Issue Date
1996-04-30
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Patent
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Abstract
The invention relates to the method of synthesis of bicyclic hexahydroaporphine compounds which may provide improved therapy for diseases characterized by an increase in intraocular pressure. More specifically, the present invention relates to the preparation of agents which may provide for improved treatment of patients with glaucoma or ocular hypertension. The present invention describes the intraocular pressure lowering capabilities of several of the bicyclic hexahydroaporphine structures.
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United States Patent Office
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