The Effect of Continuous Phase and Glass Content on Fracture Toughness and Calcium and Phosphate Ion Release from Ion Permeable Microcapsules in Glaze Formulations

Abstract

This study expands on the work of developing dental resin based restorations capable of releasing phosphate, calcium, and fluoride ions. This approach has the capability of combating recurrent caries. In an attempt to develop a glaze formulation, the role of monomer composition and glass filler incorporation on ion release was studied. Ion permeable microcapsules containing bioavailable calcium and phosphate salts integrated into various resin formulations that differ in monomer types and ratios of the continuous phase along with how the presence of silanated glass filler effects the release of remineralizing ions is measured. The objective of this research is to develop a glaze formulation that can sustain a controlled release of bioavailable calcium and phosphate ions for extended periods, ideally between prophylactic examinations. Second, mechanical testing will be conducted to see how the inclusion of ion permeable microcapsules affects the fracture toughness of the glaze, with the aim to understand how to develop a bioactive dental composite that can withstand occlusal stresses of large restorations in posterior dentition.