Device and Direct Method for Detecting Antibiotic-Inactivating Factors

dc.contributor.authorBlack, Jennifer A.
dc.contributor.authorMoland, Ellen Smith
dc.contributor.authorThomson, Kenneth S.
dc.contributor.cuauthorBlack, Jennifer A.
dc.contributor.cuauthorMoland, Ellen Smith
dc.contributor.cuauthorThomson, Kenneth S.
dc.date.accessioned2015-05-11T17:24:40Z
dc.date.available2015-05-11T17:24:40Z
dc.date.issued2010-05-18
dc.date.submitted2007-07-24
dc.description.abstractThe present invention provides a method of determining the antibiotic susceptibility of a microorganism comprising the following steps. First, a culture of the microorganism whose susceptibility is to be determined is admixed with an antibiotic to which susceptibility is to be assayed, and a permeabi- lizing agent for the microorganism present in a non-growth- inhibiting microorganism-permeabilizing effective amount to form an assay culture. Next, the assay culture is incubated under appropriate culture conditions and for a time sufficient to determine the susceptibility of the microorganism to the antibiotic. In another aspect, the present invention provides an improved method for antibiotic susceptibility testing of a microorganism in a culture by admixing the culture with an antibiotic to which susceptibility is to be assayed, and incubating the culture for a time sufficient to determine the susceptibility of the microorganism to the antibiotic, the improvement comprising admixing the culture with a perme- abilizing agent for the microorganism present in a nongrowth inhibiting microorganism-permeabilizing effective amount.en_US
dc.identifier.patentapplnumber11/880768en_US
dc.identifier.patentnumberUS 7718392 B2en_US
dc.identifier.urihttp://hdl.handle.net/10504/68623
dc.publisherUnited States Patent Officeen_US
dc.rights.holderCreighton Universityen_US
dc.titleDevice and Direct Method for Detecting Antibiotic-Inactivating Factorsen_US
dc.typePatent
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