Correlation of Vaginal and Cervical Cytology With Pathological Biopsy With Special Emphasis on the Borderline Lesion
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Authors
Luby, Robert J.
Issue Date
1959
Volume
Issue
Type
Thesis
Language
en_US
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Abstract
As a result of the interest in cervical cytologic study all degrees of epithelial abnormalities in the uterine cervix have been noted; the significance of these changes in relation to their biologic potential is not well understood. The desire to comprehend the meaning of certain of these histologic changes prompted the investigation which is described in the following paragraphs. | It is obvious to most observers that considerable confusion exists in the minds of many when presented with a cervical biopsy showing varying degrees of atypical epithelial derangement. A review of recent incidence and prevalence figures suggests that the diagnosis of in situ or intra-epithelial carcinoma of the cervix uteri is made more frequently than similar figures for invasive carcinoma would suggest is reasonable. Further comparison with mortality figures for carcinoma of the uterine cervix emphasizes this. The Joneses, commenting on a report by Kimmelsteil, Bos and Nolen, compared these authors' incidence figures for in situ carcinoma of 4.4 per thousand in the 51 to 60 age group with reported mortality rate from the National Office of Vital Statistics of .26 per thousand for carcinoma of the cervix in the same age group. Even allowing for a 50 per cent cure throughout the country these authors found eight times as many in situ cancers as can be accounted for by deaths from cancer of the cervix in the same age group.
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Publisher
Creighton University
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