Blood and Plasma Volume Determinations With the Evans Blue Dye (T-1824) Method: a Clinical Investigation With Special Reference to the Blood and Plasma Volume Changes Following Transfusions, and in the Treatment of Cardiac Decompensation
Lemire, Rosaire E. Jr.
At the present time there is shown much interest in the red cell and plasma volumes in different clinical conditions. This paper represents, first, an investigation of the Evans Blue dye (T-1824) method of determining the blood volume; and, second, an application of this method in the study of the changes in the red cell and plasma volumes following transfusions, and blood volume changes in congestive heart failure. | The first three chapters consist of a review of the different methods used in the determination of plasma and red cell volumes, and a discussion of Evans Blue dye. Because of their importance, a rather comprehensive report is made of the fate and the disappearance of T-1824 in the circulation. | The accuracy of the Evans Blue dye method is subject to criticism and In Chapter 17 on attempt is made to carefully review the critical observations reported in the literature.
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