Welcome to Creighton Digital Repository (CDR)
The CDR is an open source solution for capturing, managing, promoting, sharing, and preserving digital collections in any format. It provides both open and secure access to collections or individual items within the repository. Open CDR collections are discoverable via all the major web search engines, which makes the CDR an invaluable tool for promoting and sharing your work with the world-wide scholarly community.
Communities in Creighton Digital Repository
Select a community to browse its collections.
Recent Submissions
- Loading...
Item The Creightonian, 2024_09_06(Creighton University, 2024-09-06) - No Thumbnail Available
Item ABA Client Counseling Competition National Finals, National Semifinalist, 2023-2024(2024)ABA AMERICAN BAR ASSOCIATION Law Student Division Creighton University School of Law Stephanie Oliver and Reghan Kort National Semifinalist 2023-2024 National Client Counseling Competition - No Thumbnail Available
Item ABA Regional Client Counseling Competition, Regional Finalist, 2023-2024(2024)ABA AMERICAN BAR ASSOCIATION Law Student Division Creighton University School of Law Stephanie Oliver and Reghan Kort Regional Finalist 2023-2024 Regional Client Counseling Competition - No Thumbnail Available
Item The Rat as a Translational Model of Neurotrauma: Primary Somatosensory Input and Imaging Biomarker Validation Following Spinal Cord and Peripheral Nerve Injuries(Creighton University, 2024)Neurotrauma is a leading cause of death and disability worldwide. Trauma is inherently chaotic and difficult to study, necessitating the use of translational models that provide standardizable and quantifiable models of injury. Rats are the most commonly used models of spinal cord (SCI) and peripheral nerve (PNI) injuries because their anatomy and physiology approximates that of humans, while their size and management make them economical and practical for large scale studies. Although the CNS does not regenerate, the peripheral nervous system does. One recent strategy under investigation for SCI patients is to use nerve grafts to restore function to spinal levels below the site of lesion. Questions remain about the suitability of rodent models for studies focused on higher order, complex, spinal tracts. Furthermore, questions remain on the best methods to track recovery following nerve graft or injury, as current diagnostic and prognostic clinical tools are limited. Diffusion MRI (dMRI) has the potential to classify nerve injury severity and evaluate nerve recovery more accurately and earlier in time than current electrodiagnostics but requires validation. In this study, we evaluated the rat’s suitability as a translation model of sensory injury and recovery within the corticospinal tract (CST), the tract which controls fine hand function in primates. We chose this tract because restoration of hand function is the most cited goal among quadriplegics. Additionally, we developed and tested a method to help validate and evaluate advanced dMRI biomarkers of PNI. Our long long-term goal is to use dMRI to quantify nerve injury and recovery to aid clinical decision making and aid prognostication following PNI. We found that rats display a similar response to primates and are suitable translational models for basic questions regarding the CST’s response to a sensory dorsal root-dorsal column SCI. Additionally, using a novel nerve-specific tissue clearing and innumolableing method we developed, we were able to track axons and derive a quantitative measure of the 3D histological structure of injured nerves, called a structure tensor. We show this measure correlates to the fractional anisotropy we acquired from dMRI within our clinically relevant cut-repair PNI model. Together, this lays the foundation for future clinical validation and translation of these novel imaging biomarkers of nerve injury and recovery. - No Thumbnail Available
Item Interagency Collaboration of Agencies Supporting Homeless Veterans(Creighton University, 2024)Efforts to prevent veteran homelessness in the United States have been ongoing for decades, yet thousands of veterans still face homelessness daily. This case study explores collaborative leadership efforts among nonprofit and government agencies aimed at preventing homelessness among veterans. The research question asks how nonprofit agencies serving homeless veterans in a rural southwest community describe their interagency collaborative practices. Interviews with agency leadership, observations of meetings, and documents of meeting minutes were analyzed for codes, categories, and themes. The findings revealed five themes. 1) Agencies serving homeless veterans in a rural southwest community have a shared mission of veteran homelessness prevention. 2) Agencies serving homeless veterans in a rural southwest community need a community-wide strategic plan. 3) Agencies serving homeless veterans in a rural southwest community have positive interactions. 4) Agencies serving homeless veterans in a rural southwest community are reactive. 5) Agencies serving homeless veterans in a rural southwest community have an elementary understanding of collaboration. Recommendations for positive change included making collaborative leadership an essential component for community-wide impact for agencies serving homeless veterans; agencies serving homeless veterans must enhance communication and data sharing and fully integrate the Homeless Management Information System (HMIS); and agencies serving homeless veterans must establish SMART performance measures for the Mayor’s Task Force.